As one of the core facilities of Chinese Institute for Brain Research (CIBR), Beijing, the Imaging Facility is mainly responsible for the maintenance of optical imaging equipment, training, experimental services and the development of some new optical imaging technologies and methods. At present, Imaging Facility is equipped with Upright Laser Confocal Scanning Confocal Microscopes, Inverted Laser Confocal Scanning Confocal Microscope, Virtual Slide Microscope, Light Sheet Microscope, Two-photon Excitation Microscope, High-Throughput Cellular Screening System, Dual-disk Laser Confocal High-Content Screening System, and some other sets of equipment, which are capable to satisfy the needs of construction of the whole brain atlas, in vivo imaging, living cell imaging and high-throughput biological screening. Meanwhile, Imaging Facility staff is willing to assist in the design of a more reasonable and effective imaging scheme to obtain high-quality data and technical support for each laboratory of CIBR.